Neurologie

Cerebrale Läsionen

Feasibility and Acceptability of a Remotely Delivered Executive Function Intervention That Combines Computerized Cognitive Training and Metacognitive Strategy Training in Chronic Stroke. Jaywant, A., Mautner, L., Waldman, R., O’Dell, M. W., Gunning, F. M., & Toglia, J. (2023). International Journal of Environmental Research and Public Health, 20(9), 5714.

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Effect of RehaCom cognitive rehabilitation software on working memory and processing speed in chronic ischemic stroke patients. Amiri, S., Hassani-Abharian, P., Vaseghi, S., Kazemi,R., & Nasehi, M. (2021). Assistive Technology, 35(1), 41–47.

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The efficacy of computerized cognitive rehabilitation in improving attention and executive functions in acquired brain injury patients, in acute and postacute phase. Kim,H. S., Lim, K.-B., Yoo, J., Kim, Y. W., Lee, S. W., Son, S., Kim, C., & Kim, J. (2021). European Journal of Physical and Rehabilitation Medicine,57(4).

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A Study on the Combined Effect of Cognitive Therapy and Speech Therapy for Aphasics: Comparison of Follow-up Evaluation After Post-Treatment. Lee, J. S., Lee, J. Y., & Lee, O. B. (2021). Journal of Speech-Language & Hearing Disorders, 30(2), 61–68.

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The effect of high vs. low intensity neuropsychological treatment on working memory in patients with acquired brain injury. Weicker, J., Hudl, N., Hildebrandt, H., Obrig, H.,Schwarzer, M., Villringer, A., & Thöne-Otto, A. (2020). Brain Injury, 34(8), 1051-1060.

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Cognitive rehabilitation program to improve cognition of cancer patients treated with chemotherapy: A 3‐arm randomized trial. Dos Santos, M., Hardy‐Léger, I., Rigal, O., Licaj, I., Dauchy, S., Levy, C., Joly, F. (2020). Cancer, 126(24),5328-5336.

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Comprehensive cognitive training improves attention and memory in patients with severe or moderate traumatic brain injury. Leśniak MM, Iwański S, Szutkowska-Hoser J, Seniów J. Applied Neuropsychology 2019 Mar:Adult, DOI: 10.1080/23279095.2019.1576691

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Effects of group versus individual therapy for patientswith memory disorder after an acquired brain injury: A randomized, controlledstudy. Leśniak, M. M., Mazurkiewicz, P., Iwański, S., Szutkowska-Hoser,J., & Seniów, J. (2018). Journal of Clinical and ExperimentalNeuropsychology, 40(9), 853–864. 

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Improving Everyday Memory Performance After Acquired Brain Injury: An RCT on Recollection and Working Memory Training KM Richter, C Mödden, P Eling and H Hildebrandt. Online First Publication, April 26, 2018., doi.org/10.1037/neu0000445

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Effectiveness of a Computer-Based Training Program of Attention and Memory in Patients with Acquired Brain Damage Fernandez E, Bergado Rosado JA, Rodriguez Perez D, Salazar Santana S, Torres Aguilar M, Bringas ML Behavioral Sciences (Basel). 2017 Dec 30;8(1). pii: E4. doi: 10.3390/bs8010004

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Clinical Efficacy of Acupuncture Treatment in Combination With RehaCom Cognitive Training for Improving Cognitive Function in Stroke: A 2× 2 Factorial Design Randomized Controlled Trial Jiang C, Yang S, Tao J, Huang J, Li Y, Ye H, Chen S, Hong W, Chen L J Am Med Dir Assoc. 2016 Aug 31.pii: S1525-8610(16)30299-7. doi: 10.1016/j.jamda.2016.07.021. Epub 2016 Aug 31

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Effects of neurofeedback and computer-assisted cognitive rehabilitation on relative brain wave ratios and activities of daily living of stroke patients: a randomized control trial Cho HY, Kim KT, Jung JH J Phys Ther Sci. 2016 Jul; 28(7): 2154–2158. Published online 2016 Jul 29. doi: 10.1589/jpts.28.2154

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Recovery after brain damage: Is there any indication for generalization between different cognitive functions? Richter KM, MöddenC, Hanken K, Hildebrandt H J Clin Exp Neuropsychol. 2015;37(6):571-80. Doi:10.1080/­13803395.2015.1030358. Epub 2015 Jun 10

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Effect of computerized cognitive rehabilitation program on cognitive function and activities of living in stroke patients Yoo C, Yong MH, Chung J, Yang Y J Phys Ther Sci. 2015 Aug;27(8):2487-9. doi: 10.1589/jpts.27.2487. Epub 2015 Aug21.

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Working memory training and semantic structuring improves remembering future events, not past events. Richter KM, MSc, Mödden C, MSc, Eling P, PhD, Hildebrandt H, Prof. Neurorehabil Neural Repair. 2015 Jan; 29(1):33-40. doi: 10.1177/1545968314527352. Epub 2014 Apr 2.

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The effectiveness of computer-assisted cognitive rehabilitation in brain-damaged patients Łojek E, Bolewska A Polish Psychological Bulletin 2013, vol. 44(1), 31-39 DOI -10.2478/ppb-2013-0004

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Clinical Impact of RehaCom Software for Cognitive Rehabilitation of Patients with Acquired Brain Injury International Neurological Restoration Center (CIREN 2012) Fernández E, Bringas ML,Salazar S, Rodríguez D, García ME, Torres M.MEDICC Rev. 2012 Oct; 14(4):32-5.

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A Randomized Controlled Trial Comparing 2 Interventions for Visual Field Loss With Standard Occupational Therapy During Inpatient Stroke Rehabilitation FMödden C, Behrens M, Damke I, Eilers N, Kastrup A, Hildebrandt H Neurorehabil Neural Repair. 2012 Jun;26 (5):463-9. doi:10.1177/1545968311425927. Epub 2011 Dec 2

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Is the Neuropsychological Treatment of Memory Specific or Unspecific? – Comparing Treatment Effects on Memory and Attention. Spahn V, Kulke H, Kunz M, Thöne-Otto A, Schupp W, Lautenbacher S Source, 2010; Zeitschrift für Neuropsychologie, 21 (4), 2010, 239-245

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Attention remediation following traumatic brain injury in childhood and adolescence. Galbiati S, Recla M, Pastore V, Liscio M, Bardoni A, Castelli E, Strazzer S Neuropsychology. 2009 Jan;23(1):40-9. doi:10.1037/a0013409.

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The Effects of a Computer-assisted Cognition Training Program (RehaCom®) in Stroke Patients Sung Hun Shin, M.D., Ji Sung Kim, M.D. and Yong Kyun Kim, M.D. Brain & NeuroRehabilitation Vol. 1, No. 2, September, 2008

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Cognitive disorders following Covid19 Infection. The Leipzig Treatment Program for Interdisciplinary Diagnosis and Therapy of Neurocognitive Post-COVID Symptoms: Experiences and Preliminary Results. Hasting, A. S., Herzig, S., Obrig, H., Schroeter, M.L., Villringer, A., & Thöne-Otto, A. I. T. (2023). Zeitschrift Für Neuropsychologie, 34(2), 71–83. 

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Improved cognitive performance, increased theta, alpha,beta and decreased delta powers after cognitive rehabilitation augmented with tDCS in a patient with post-COVID-19 cognitive impairment (brain-fog). Wysokiński, A., Szczepocka, E., & Szczakowska, A. (2023).Psychiatry Research Case Reports, 2(2), 100164. 

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Systematische Reviews & Metaanalysen. The effects of computer‐assisted cognitive rehabilitation on cognitive impairment after stroke: A systematic review and meta‐analysis. Nie, P., Liu, F., Lin, S., Guo, J., Chen, X., Chen, S., Yu, L., & Lin, R. (2022). Journal of Clinical Nursing,31(9–10), 1136–1148.

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Efficacy of computerized cognitive training on improving cognitive functions of stroke patients: A systematic review and meta‐analysis of randomized controlled trials. Zhou, Y., Feng, H., Li, G., Xu, C., Wu, Y., & Li, H. (2022). International Journal of Nursing Practice, 28(3),e12966. 

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Evidence-Based Cognitive Rehabilitation: Systematic Review of the Literature From 2009 Through 2014 Cicerone KD, Goldin Y, Ganci K, Rosenbaum A, Wethe JV, Langenbahn DM, Malec JF, Bergquist TF, Kingsley K, Nagele D, Trexler L, Fraas M, Bogdanova Y, HarleyJP. Arch Phys Med Rehabil. 2019 Aug;100(8):1515-1533. doi:10.1016/j.apmr.2019.02.011.

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Can impaired working memory functioning be improved by training? A meta-analysis with a special focus on brain injured patients. Weicker J, Villringer A, Thöne-Otto A Neuropsychology. 2016 Feb;30(2):190-212.doi: 10.1037/neu0000227

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Multiple Sklerose

Motor, cognitive, and combined rehabilitation approaches on MS patients’ cognitive impairment. Argento, O., Piacentini, C., Bossa, M., Caltagirone, C., Santamato, A., Saraceni, V., & Nocentini, U. (2023). Neurological Sciences, 44(3), 1109–1118. 

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Fatigue, cognition and inflammatory biomarkers changes in response to computer-based cognitive training in multiple sclerosis patients: A randomized controlled trial. Moustafa, E. B. S., Darwish, M. H., El-Tamawy, M. S., & Abu Elkasem, S. T. (2022). NeuroRehabilitation, 51(2),315–324. 

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RehaCom rehabilitation training improves a wide-range ofc ognitive functions in multiple sclerosis patients. Naeeni Davarani, M., Arian Darestani, A., Hassani-Abharian, P., Vaseghi, S., Zarrindast, M.-R., & Nasehi, M. (2022). Applied Neuropsychology: Adult, 29(2), 262–272.

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Influence of RehaCom Therapy on the Improvement of Manual Skills in Multiple Sclerosis Subjects. Pawlukowska, W., Dobrowolska, N., Szylinska, A., Koziarska, D., Meller, A., Rotter, I., & Nowacki, P. (2020). Annals of rehabilitation medicine, 44(2), 142–150.

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Do Secondary Progressive Multiple Sclerosis Patients Benefit From Computer-Based Cognitive Neurorehabilitation? A Randomized Sham Controlled Trial Lambros Messinis, Mary H Kosmidis, Grigorios Nasios, Spyridon Konitsiotis, Aikaterini Ntoskou, Christos Bakirtzis, NikolaosGrigoriadis, Panayiotis Patrikelis, Elias Panagiotopoulos, Philippos Gourzis, Sonia Malefaki, Panagiotis Papathanasopoulos
January 2020, online ahead of print

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Improving Everyday Memory Performance After Acquired Brain Injury: An RCT on Recollection and Working Memory Training Efficacyof a Computer-Assisted Cognitive Rehabilitation Intervention in Relapsing-Remitting Multiple Sclerosis Patients: A Multicenter Randomized Controlled Trial

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A Randomised Controlled Trial of Efficacy of Cognitive Rehabilitation in Multiple Sclerosis: A Cognitive, Behavioural, and MRI Study Campbell J, Langdon D, Cercignani M, Rashid W Hindawi PublishingCorporation Neural Plasticity Volume 2016, Article ID 4292585, 9 pages

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Two Years Follow up of Domain Specific Cognitive Trainingin Relapsing Remitting Multiple Sclerosis: A Randomized Clinical Trial Mattioli F, Bellomi F, Stampatori C, Provinciali L, Compagnucci L, Uccelli A, Pardini M, Santuccio G, Fregonese G, Pattini M, Allegri B, ClericiR, Lattuada A, Montomoli C, Corso B, Gallo P, Riccardi A, Ghezzi A, Roscio M, Tola MR, Calanca C, Baldini D, Trafficante D, Capra R; Front Behav Neurosci. 2016 Feb 23;10:28. doi: 10.3389/fnbeh.2016.00028.

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Persistence of the effects of attention and executivefunctions intensive rehabilitation in relapsing remitting multiple sclerosis Mattioli F, Stampatori C, Scarpazza C, Parrinello G, Capra R Multiple Sclerosis and Related Disorders 2012 Oct;1(4):168-73. doi:10.1016/j.msard.2012.06.004.

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Computer-Assisted Cognitive Rehabilitation of Attention Deficits for Multiple Sclerosis: A Randomized Trial With fMRI Correlates Cerasa A, Gioia MC, Valentino P, Nisticò R, Chiriaco C, Pirritano D, Tomaiuolo F, Mangone G, Trotta M, Talarico T, Bilotti G, QuattroneA.; Neurorehabil Neural Repair. 2013 May; 27(4):284-95. doi:10.1177/1545968312465194. Epub 2012 Nov 27.

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Efficacy and Specificity of intensive cognitive Rehabilitation of Attention and executive Functions in Multiple Sclerosis Mattioli F, Stampatori C, Zanotti D, Parrinello G, Capra R J; Neurol Sci. 2010 Jan 15; 288(1-2):101-5. doi: 10.1016/j.jns.2009.09.024. Epub2009 Oct 13.

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Computer-assisted memory retraining of patients with multiple sclerosis Mendozzi L, Pugnetti L, Motta A, Barbieri E, Gambini A, Cazzullo CL;The Italian Journal of Neurological Sciences; November 1998, Volume 19,Supplement 6, pp S431–S43

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Systematische Reviews & Metaanalysen. Computer-assisted cognitive rehabilitation inneurological patients: State-of-art and future perspectives. Maggio, M.G., De Bartolo, D., Calabrò, R. S., Ciancarelli, I., Cerasa, A., Tonin, P., DiIulio, F., Paolucci, S., Antonucci, G., Morone, G., & Iosa, M. (2023). Frontiers in Neurology, 14, 1255319. 

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Cognitive Rehabilitation in Multiple Sclerosis in the Period from 2013 and 2021: A Narrative Review. Brochet, B. (2021). Brain Sciences, 12(1), 55.

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Neurological update: Cognitive rehabilitation in multiple sclerosis. Chen, M. H., Chiaravalloti, N. D., & DeLuca, J. (2021). Journal of Neurology, 268(12), 4908–4914. 

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Treatment and management of cognitive dysfunction inpatients with multiple sclerosis. DeLuca, J., Chiaravalloti, N. D., & Sandroff, B. M. (2020). Nature Reviews Neurology, 16(6), 319–332. 

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New aspects of symptomatic MS treatment: Part 6 – cognitive dysfunction and rehabilitation Henze T, Feneberg W, FlacheneckerP, Seidel D, Albrecht H, Starck M, Meuth SG; Der Nervenarzt, April 2018, Volume 89, Issue 4, pp 453–459

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Cognitive Rehabilitation in Multiple Sclerosis: The Role of Plasticity Chiaravalloti ND, Genova HM, DeLuca J Front Neurol. 2015; 6:67. Published online 2015 Apr 2. doi: 10.3389/fneur.2015.00067

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Parkinson

The beneficial effects of computer-based cognitive training in Parkinson’s disease: A systematic review. Nousia, A., Martzoukou, M., Tsouris, Z., Siokas, V., Aloizou, A.-M., Liampas, I., Nasios,G., & Dardiotis, E. (2020). Archives of Clinical Neuropsychology, 35(4),434–447.

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Metaanalyse. Cognitive training in Parkinson disease: A systematicreview and meta-analysis Leung IH, Walton CC, Hallock H, Lewis SJ, Valenzuela M, Lampit A; Neurology published online October 30, 2015 DOI10.­1212/­WNL.­0000000000002145

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Psychiatrie

Schizophrenie

The efficacy of computer-based cognitive training for executive dysfunction in schizophrenia Mak M, Tyburski E, Starkowska A, Karabanowicz E, Samochowiec A, Samochowiec J Psychiatry Res. 2019 Jul1;279:62-70. doi: 10.1016/j.psychres.2019.06.041

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The implementation of cognitive remediation interventions in Campania Palumbo D, Patriarca S, Mucci A, De Angelis M, Di Crosta I, Piegari G, Galderisi S JOURNAL OF PSYCHOPATHOLOGY, 2018; 24:98-103

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Preliminary study of a rehabilitation program based on attentional processes to treat auditory hallucinations López-Luengo B, Muela-Martínez JA Cogn Neuropsychiatry. 2016 Jul;21(4):315-334. Epub 2016 Jul18.

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The effectiveness of computerized cognitive rehabilitation training program in improving cognitive abilities of schizophrenia clients Mohammadi MR, Keshavarzi Z, Talepasand S Iran J Psychiatry. 2014 Oct;9(4):209-15.

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The efficacy of cognitive neurorehabilitation with RehaCom program in schizophrenia patients Mak M, Tybura P, Bieńikowski P, Karakiewicz B, Samochowiec J Psychiatr Pol. 2013 Mar-Apr;47(2):213-23

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How can cognitive remediation therapy modulate brainactivations in schizophrenia? An fMRI study Bor J, Brunelin J, d‘Amato T, Costes N, Suaud-Chagny M, Saoud M, Poulet E; June 30, 2011 Volume 192, Issue 3, Pages 160–166

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A randomized, controlled trial of computer-assisted cognitive remediation for schizophrenia d‘Amato T, Bation R, Cochet A, Jalenques I, Galland F, Giraud-Baro E, Pacaud-Troncin M, Augier-Astolfi F, Llorca PM, Saoud M, Brunelin J Schizophr Res. 2011 Feb; 125(2-3):284-90. doi:10.1016/j.schres.2010.10.023. Epub 2010 Nov 19.

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Depression

Efficacy of Neurocognitive Remediation Therapy During an Acute Depressive Episode and Following Remission: Results From Two Randomised Pilot Studies Semkovska M, Ahern E, Lonargáin DO, Lambe S, McLaughlin DM European Psychiatry, Volume 30, Supplement 1, 28–31 March 2015, Pages 403

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Systematische Reviews & Metaanalysen. Cognitive rehabilitation for improving cognitivefunctions and reducing the severity of depressive symptoms in adult patientswith Major Depressive Disorder: A systematic review and meta-analysis ofrandomized controlled clinical trials. Mokhtari, S., Mokhtari, A., Bakizadeh, F., Moradi, A., & Shalbafan, M. (2023). BMC Psychiatry, 23(1),1–18. 

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The efficacy of cognitive remediation in depression: A systematic literature review and metaanalysis. Therond, A., Pezzoli, P., Abbas, M., Howard, A., Bowie, C. R., & Guimond, S. (2021). Journal of Affective Disorders, 284, 238–246.

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Kinder und Jugendliche

ADHS

Evaluation of a computer-based neuropsychological Training in Children with Attention-Deficit Hyperactivity Disorder (ADHD). Amonn F, Frölich J, Breuer D, Banaschewski T, Doepfner M; NeuroRehabilitation. 2013;32(3):555-62. doi: 10.3233/NRE-130877

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Kognitive Störungen im Kindesalter

The efficacy of cognitive training programs in children and adolescents: a meta-analysis. Karch D, Albers L, Renner G, Lichtenauer N, von Kries R Deutsches Ärzteblatt Int. 2013 Sep;110(39):643-52. doi: 10.3238/arztebl.2013.0643. Epub 2013 Sep 27.

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Geriatrie

Mild Cognitive Impairment (MCI)

Evaluation of the Efficacy and Feasibility of a Telerehabilitation Program Using Language and Cognitive Exercises in Multi-Domain Amnestic Mild Cognitive Impairment. Nousia, A., Pappa, E., Siokas, V., Liampas, I., Tsouris, Z., Messinis, L., Patrikelis, P., Manouilidou, C., Dardiotis, E., & Nasios, G. (2023). Archives of ClinicalNeuropsychology, 38(2), 224–235. 

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Demenz

Computer-Based Cognitive Training vs. Paper-and-Pencil Training for Language and Cognitive Deficits in Greek Patients with Mild Alzheimer’s Disease: A Preliminary Study. Georgopoulou, E.-N., Nousia, A., Siokas, V., Martzoukou, M., Zoupa, E., Messinis, L., Dardiotis, E., &Nasios, G. (2023). Healthcare, 11(3), 443. 

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Beneficial effect of computer-based multidomain cognitivetraining in patients with mild cognitive impairment. Nousia, A., Martzoukou, M., Siokas, V., Aretouli, E., Aloizou, A. M., Folia, V., & Dardiotis, E. (2019). Applied Neuropsychology: Adult, 1-10.

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Beneficial Effect of Multidomain Cognitive Training onthe Neuropsychological Performance of Patients with Early-Stage Alzheimer’s Disease. Nousia A, Siokas V, Aretouli E, Messinis L, Aloizou AM, Martzoukou M, Karala M, Koumpoulis C, Nasios G, Dardiotis EHindawi, Neural Plasticity, Volume 2018, Article ID 2845176, doi.org/10.1155/2018/2845176

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The Effects of Cognitive Rehabilitation Training on Cognitive Function of Elderly Dementia Patients. Oh BH, Kim YK, Kim JH, Shin YS J Korean Neuropsychiatr. Assoc. 2003, Vol 42, No4, 514-519

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Systematische Reviews & Metaanalysen. Computerized Cognitive Training in Older Adults With Mild Cognitive Impairment or Dementia: A Systematic Review and Meta-Analysis. Hill NT, Mowszowski L, Naismith SL, Chadwick VL, Valenzuela M, Lampit; A The American journal of psychiatry 2017 Apr 1;174(4):329-340. doi:10.1176/­appi.ajp.­2016.16030360

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Studien mit Gesunden

Arbeitsgedächtnis

WOME: Theory-Based Working Memory Training - A Placebo-Controlled, Double-Blind Evaluation in Older Adults Weicker J, Hudl N, Frisch S, Lepsien J, Mueller K, Villringer A, Thöne-Otto A Front Aging Neurosci. 2018 Aug 14;10:247. doi: 10.3389/fnagi.2018.00247. eCollection 2018

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Aufmerksamkeit und Arbeitsgedächtnis

Effect of Multimodal Intervention (computer based cognitive training, diet and exercise) in comparison to health awareness among older adults with Subjective Cognitive Impairment (MISCI-Trial) — A Pilot Randomized Control Trial. Chatterjee, P., Kumar, D. A., Naqushbandi, S., Chaudhary, P., Khenduja, P., Madan, S., Fatma, S., Khan, M. A., & Singh, V.(2022). PLOS ONE, 17(11), e0276986. 

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Attention and Working Memory Training: The Effect of RehaCom Software on Cognitive Skills in a Non-Clinical Sample. Miruna C Barbu, Róisín M Furlong, Blanca Poveda and Jen Scotland University of Edinburgh, Edinburgh, UKNHS Lothian, Clinical Neuropsychology Department, Astley Ainslie Hospital, Edinburgh, UK, Published: June 27, 2017

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Prospektives Gedächtnis

Stress-related cortisol responsivity modulates prospective memory Glienke K, Piefke; MJournal of Neuroendocrinology 2017Dec;29(12). doi: 10.1111/jne.12544.

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Acute social stress before the planning phase improves memory performance in a complex real life-related prospective memory task Glienke K, Piefke M; Neurobiol Learn Mem. 2016 Sep;133:171-81. doi:10.1016/j.nlm.2016.06.025. Epub 2016 Jun 28.

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Gedächtnis

Memory enhancement in healthy older adults using a brain plasticitybased training program: a randomized, controlled study. Mahncke HW, Connor BB, Appelman J, Ahsanuddin ON, Hardy JL, Wood RA, Joyce NM, BoniskeT, Atkins SM, Merzenich MM. Proc Natl Acad Sci U S A. 2006 Aug15;103(33):12523-8. Epub 2006 Aug 3.

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Screenings

Impact of Fatigue on Cognitive Function in Post-COVID19 Survivors. Abdelmagid, E. R., Fahmy, E. M., Taha, S. I., & Elrewainy, R. M. (2022). NeuroQuantology, 20(8), 7868–7874.

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Cognitive impairment during subacute rehabilitation period in patients after COVID-19 infection. Avota, R. K. (2022).

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